Table 5.
ROC analysis of the diagnostic performance for different parameters and methods alone or in combination for distinguishing benign and malignant groups, and distinguishing AC and SCC groups.
| Parameters | Cutoff | AUC | P Value | Youden index | Accuracy | Sensitivity | Specificity | 95%CI | |
|---|---|---|---|---|---|---|---|---|---|
| Benign and Malignant groups | |||||||||
| ADC(μm2/ms) | 1.36 | 0.760 | <0.0001 | 0.3974 | 74.1 | 80.00 | 59.74 | 0.670 - 0.836 | |
| μ(μm) | 5.85 | 0.824 | <0.0001 | 0.5818 | 72.3 | 82.86 | 75.32 | 0.741 - 0.890 | |
| D(μm2/ms) | 1.53 | 0.821 | <0.0001 | 0.5221 | 73.2 | 74.29 | 77.92 | 0.737 - 0.887 | |
| β | 0.69 | 0.585 | 0.1534 | / | / | / | / | 0.488 - 0.677 | |
| SUVmax | 6.85 | 0.801 | <0.0001 | 0.5714 | 72.3 | 85.71 | 71.43 | 0.715 - 0.870 | |
| μ + D | 0.66 | 0.825 | <0.0001 | 0.5818 | 71.4 | 82.86 | 75.32 | 0.742 - 0.890 | |
| Combined Diagnosis a | 0.79 | 0.872 | <0.0001 | 0.6727 | 76.8 | 97.14 | 70.13 | 0.796 - 0.928 | |
| AC and SCC groups | |||||||||
| ADC(μm2/ms) | 1.51 | 0.747 | <0.0001 | 0.3850 | 69.2 | 42.50 | 96.00 | 0.624 - 0.847 | |
| μ(μm) | 7.33 | 0.911 | <0.0001 | 0.7000 | 83.1 | 90.00 | 80.00 | 0.814 - 0.967 | |
| D(μm2/ms) | 1.43 | 0.897 | <0.0001 | 0.6500 | 80.0 | 85.00 | 80.00 | 0.796 - 0.959 | |
| β | 0.73 | 0.664 | 0.0162 | 0.3050 | 64.6 | 42.50 | 88.00 | 0.536 - 0.776 | |
| SUVmax | 12.36 | 0.648 | 0.0413 | 0.2900 | 66.2 | 85.00 | 44.00 | 0.520 - 0.762 | |
| μ + β + D | 0.58 | 0.908 | <0.0001 | 0.7100 | 84.6 | 95.00 | 76.00 | 0.810 - 0.966 | |
| Combined Diagnosis b | 0.42 | 0.922 | <0.0001 | 0.7400 | 86.2 | 90.00 | 84.00 | 0.828 - 0.974 | |
a
The combined diagnosis represents μ + D + ADC + SUVmax.
b
The combined diagnosis represents μ + β + D + ADC + SUVmax.
AUC, Area Under the Curve.