Fig. 4.

oxNaCl and cmc equally reduce tumor burden in ovo and in a syngeneic model of peritoneal carcinomatosis in vivo. (A) Schematic overview of experimental treatment procedure in ovo. (B) Representative images of excised in ovo tumors. (C) Assessment of tumor weight of in ovo tumor cell–DC coculture tumors. (D) Schematic overview of experimental treatment procedure in vivo. (E) Representative images of TUNEL-stained tumor nodules indicative for apoptosis with representative distance marks of penetration depths and quantification thereof (Insert: y axis shows penetration depth with regard to dead cell regions reaching within the tissues expressed in micrometers). (F) Tumor weight of excised peritoneal tumor nodules. Graphs show mean. Statistical analysis was performed using one-way ANOVA (*P < 0.05, **P < 0.01, ***P < 0.001; ns, nonsignificant). (Scale bar, 1 mm.) moDC, monocyte-derived DCs.