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. Author manuscript; available in PMC: 2022 Aug 4.
Published in final edited form as: J Psychiatr Res. 2020 Oct 8;132:72–83. doi: 10.1016/j.jpsychires.2020.09.028

Table 4.

provides information on clusters under the effect of group where dACC modulation is predicted by lifetime obsessive or lifetime compulsive symptom dimensions. These clusters are represented in Figure 3.

Compulsion / Working Memory

Positive Negative


AAL MNI Coordinates Cluster Extent T Score P (peak) AAL MNI Coordinates Cluster Extent T Score P (peak)
Precentral_L −50 −1 41 826 3.77 <0.001 Postcentral_L −52 −20 26 177 2.68 0.006

Occipital_Sup_L −24 −73 32 1650 3.70 0.001 Temporal_Mid_R 33 −52 20 65 2.23 0.017

Postcentral_R 58 −2 34 689 3.35 0.001 Precuneus_R 14 −54 38 54 2.16 0.020

Precentral_R 42 −1 48 488 3.10 0.002 - - - - -

Frontal_Inf_Tri_R 48 29 24 402 2.78 0.005 - - - - -

Occipital_Mid_R 34 −67 23 312 2.72 0.006 - - - - -

SupraMarginal_L −62 −43 29 201 2.63 0.007 - - - - -

Caudate_L −24 −26 24 116 2.56 0.008 - - - - -

Frontal_Inf_Tri_L −48 28 28 58 2.55 0.008 - - - - -

Parietal_Inf_R 30 −52 52 159 2.54 0.009 - - - - -

Calcarine_R 9 −90 11 58 2.43 0.011 - - - - -

Putamen_R 28 8 12 50 2.40 0.012 - - - - -

Cingulum_Mid_L 0 −40 54 124 2.26 0.016 - - - - -

Calcarine_R 18 −48 6 50 2.23 0.017 - - - - -

Putamen_L −24 −2 12 75 2.22 0.017 - - - - -

Frontal_Inf_Oper_R 45 10 14 78 2.17 0.019 - - - - -

Precuneus_R 15 −66 34 102 2.17 0.019 - - - - -

Calcarine_L −20 −58 14 87 2.17 0.019 - - - - -

Obsession / Working Memory

Positive Negative


AAL MNI Coordinates Cluster Extent T Score P (peak) AAL MNI Coordinates Cluster Extent T Score P (peak)


Precuneus_L −14 −60 50 1113 3.80 <0.001 Occipital_Mid_R 44 −76 29 195 3.49 0.001

Frontal_Mid_R 46 2 52 192 3.17 0.002 Insula_L −34 −19 11 1552 3.48 0.001

Parietal_Inf_R 30 −52 52 454 3.08 0.002 Frontal_Sup_Medial_L −6 42 48 1614 2.95 0.003

Precentral_L −45 −2 42 92 2.77 0.005 Temporal_Sup_R 66 −25 16 285 2.62 0.007

Insula_L −24 −30 26 65 2.70 0.006 Cingulum_Ant_L −8 11 28 416 2.40 0.012

- - - - - Occipital_Mid_L −40 −73 26 143 2.26 0.016

- - - - - Cuneus_R 15 −86 26 139 2.25 0.017

- - - - - Insula_L −34 5 8 115 2.24 0.017

- - - - - Angular_R 38−48 22 78 2.20 0.018

- - - - - Cuneus_R 22 −70 26 64 2.04 0.025

Compulsion / Motor Control

Positive Negative


AAL MNI Coordinates Cluster Extent T Score P (peak) AAL MNI Coordinates Cluster Extent T Score P (peak)


Precentral_R 33 −4 44 127 2.91 0.004 Frontal_Mid_R 42 23 47 66 3.08 0.002

Cingulum_Mid_R 4 16 40 169 2.90 0.004 SupraMarginal_R 44 −38 23 394 2.61 0.007

Frontal_Sup_R 20 36 35 50 2.76 0.005 Rolandic_Oper_L −40 −31 20 181 2.60 0.008

SupraMarginal_L −56 −25 26 149 2.47 0.010 Frontal_Inf_Oper_L −28 14 26 318 2.59 0.008

SupraMarginal_R 54 −24 30 73 2.46 0.010 SupraMarginal_L −54 −48 24 168 2.47 0.010

Temporal_Mid_R 50 −60 16 118 2.34 0.014 Frontal_Inf_Tri_R 32 22 23 250 2.43 0.011

Occipital_Mid_R 30 −76 328 2.10 0.023 Angular_L −30 −54 28 201 2.40 0.012

- - - - - Frontal_Sup_Medial_R 4 32 53 75 2.28 0.015

- - - - - Angular_R 46 −64 38 96 2.02 0.026

Obsession / Motor Control

Positive Negative


AAL MNI Coordinates Cluster Extent T Score P (peak) AAL MNI Coordinates Cluster Extent T Score P (peak)


Postcentral_R 57 −22 34 981 4.02 <0.001 Frontal_Inf_Oper_L −28 10 26 306 3.84 <0.001

Frontal_Mid_R 38 −2 52 820 3.67 0.001 Angular_L −36 −44 26 889 2.97 0.003

SupraMarginal_L −60 −24 24 361 3.62 0.001 Occipital_Sup_R 18 −91 28 144 2.47 0.010

Cingulum_Mid_R 8 12 35 347 3.45 0.001 Cuneus −10 −85 30 164 2.45 0.011

Postcentral_R 12 −43 60 762 3.43 0.001 Angular_R 40 −61 26 259 2.44 0.011

Parietal_Sup_L −26 −52 64 458 3.35 0.001 - - - - -

Frontal_Sup_R 20 36 35 319 3.24 0.002 - - - -

Precentral_L −33 −10 44 58 3.17 0.002 - - - - -

Precentral_L −50 −2 42 124 3.08 0.002 - - - - -

Cingulum_Ant_R 9 28 24 257 3.07 0.002 - - - - -

Precentral_R 52 5 34 131 2.53 0.009 - - - - -

Occipial_Mid_L −32 −73 12 161 2.51 0.009 - - - - -

Frontal_Inf_Oper_R 45 20 30 116 2.38 0.012 - - - - -