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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: J Pain. 2021 Oct 20;23(3):450–458. doi: 10.1016/j.jpain.2021.09.007

Table 3.

Pre-Operative Factors Associated with High Impact or Bothersome Chronic Pain after Total Joint Arthroplasty

Variable High Impact Chronic Pain
(n = 216 cases, n = 1273 controls)
Bothersome Chronic Pain
(n = 520 cases, n = 1273 controls)
Knee arthroplasty
(ref: Hip)
1.48
(95% CI = 1.07-2.04)
1.40
(95% CI = 1.12-1.76)
Shoulder arthroplasty
(ref: Hip)
1.56
(95% CI = 0.89-2.75)
1.88
(95% CI = 1.29-2.74)
Female
(ref: Male)
1.09
(95% CI = 0.81-1.47)
1.36
(95% CI = 1.10-1.68)
Tobacco current or past
(Ref: No History)
1.30
(95% CI = 0.96-1.76)
1.25
(95% CI = 1.01-1.55)
Race
(Ref: White/Caucasian)
2.00
(95% CI = 1.22-3.28)
2.13
(95% CI = 1.47-3.08)
More than one surgery
(Ref: One surgery)
0.76
(95% CI = 0.48-1.20)
0.99
(95% CI = 0.73-1.34)
Time from surgery to survey
(Ref: more than 24)
1.40
(95% CI = 1.02-1.93)
1.13
(95% CI = 0.90-1.42)
Pre-operative pain score
(Ref: 4/10 or lower)
1.53
(95% CI = 1.13-2.07)
1.08
(95% CI = 0.94-1.46)
Age at first surgery
(Ref: 65 or older)
1.58
(95% CI = 1.15-2.16)
1.17
(95% CI = 0.68-1.06)
BMI
(Ref: less than 30.0)
1.31
(95% CI = 0.97-1.77)
1.11
(95% CI = 0.89-1.37)
Comorbidity
(Ref: 0-1)
1.80
(95% CI = 1.23-2.65)
1.19
(95% CI = 0.88-1.61)

• Completed cases approach was used after missing values analyses indicated patterns of missing at random

• Sample size for cases and controls correspond with total number of individuals providing data for the regression model. In both models controls were the same individuals

• Odds ratios are adjusted for all other variables