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. Author manuscript; available in PMC: 2022 Aug 4.
Published in final edited form as: Drug Deliv Transl Res. 2021 Jan 11;12(1):197–212. doi: 10.1007/s13346-021-00897-7

Table 3.

Validation parameters (inter- and intra-day precision and accuracy) of the HPLC method

Expected conc. (μg/mL) Intra-day (n = 6)
 Inter-day (n = 9)
Measured conc (μg/mL, mean ± SD) Accuracy (%, mean ± SD) %CV Measured conc (μg/mL, Mean ± SD) Accuracy (%, mean ± SD) %CV
0.1   0.11 ± 0.01 111.17 ± 5.13 4.62   0.11 ± 0.01 109.78 ± 5.05 4.60
1.0   1.01 ± 0.00 101.14 ± 0.18 0.17   1.01 ± 0.00 102.61 ± 0.29 0.29
25 24.89 ± 0.02   99.55 ± 0.07 0.07 24.91 ± 0.05 101.34 ± 0.19 0.19

Conc. concentration, SD standard deviation, CV coefficient of variation