Table 1.

Comparisons of cell diameter of DRG neurons responding to press stimuli in saline-treated controls and cisplatin-treated animals

Press responses
Diameter	Saline	Cisplatin
100-g pinch: number of activated cells (proportion of activated cells)
Small (<20 µm)	22.00 ± 4.51, n = 3 (55.9 ± 8.4%)	46.33 ± 7.75, n = 3 (67.6 ± 3.8%)
Medium (20–25 µm)	12.67 ± 3.53, n = 3 (33.6 ± 8.7%)	17.67 ± 2.40, n = 3 (25.2 ± 0.2%)
Large (>25 µm)	4.00 ± 0.58, n = 3 (10.5 ± 2.0%)	4.33 ± 2.19, n = 3 (7.2 ± 3.7%)
300-g pinch: number of activated cells (proportion of activated cells)
Small	40.33 ± 5.90, n = 3 (53.4 ± 6.7%)	52.00 ± 12.12, n = 3 (51.9 ± 12.7%)
Medium	23.67 ± 2.03, n = 3 (31.6 ± 3.4%)	29.67 ± 6.12, n = 3 (29.4 ± 18.7%)
Large	11.33 ± 2.33, n = 3 (15.0 ± 3.6%)	19.00 ± 8.62, n = 3 (18.7 ± 7.9%)
600-g pinch: number of activated cells (proportion of activated cells)
Small	49.00 ± 15.72, n = 3 (51.2 ± 7.5%)	64.00 ± 7.77, n = 3 (49.5 ± 5.6%)
Medium	26.33 ± 2.96, n = 3 (31.4 ± 5.6%)	41.67 ± 2.03, n = 3 (32.0 ± 2.1%)
Large	15.00 ± 2.52, n = 3 (17.4 ± 3.1%)	23.67 ± 5.36, n = 3 (18.4 ± 4.3%)

Most activated neurons were small (<20 µm) or medium (20–25 µm) diameter. Strong mechanical stimuli (300- and 600-g press) activated a higher proportion of large diameter (>25 µm) neurons. Proportions of small versus medium versus large diameter neurons were not statistically distinguishable between groups. N, numbers of DRGs analyzed for cell diameter.