Figure 4. Differential effect of hypoxia on proliferation and apoptosis within CD45 and PDGFRα subsets.

A) Representative flow analysis plots of CD45⁺ cells or B) PDGFRα⁺ and percentage of cells which have incorporated EdU C) Quantification of flow analysis for CD45⁺;EdU⁺ and PDGFRα⁺;EdU⁺ cells. D) Representative flow analysis plots of CD45⁺ cells or E) PDGFRα⁺ and percentage of TUNEL⁺ cells F) Quantification of flow analysis for CD45⁺;TUNEL⁺ and PDGFRα⁺;TUNEL⁺ cells. BMSCs isolated from 2–3M old male and female mice, n≥3 for each condition. One-way ANOVA, post-hoc Tukey’s multiple comparisons test, significance p < 0.05.