Table 3.
Clinical Outcomes in Patients with Moderate-Risk TA-TMA
| Outcome | Value |
|---|---|
| MODS, n (%) | 19 (42.2) |
| PICU admission, n (%) | 26 (54.2) |
| RRT, n (%) | 9 (18.8) |
| Lowest cystC GFR in patients without RRT, mL/min, median (range) | 50 (30.8–65.5) |
| Refractory hypertension requiring continuous medication infusion, n (%) | 3 (6.2) |
| Pericardial effusion requiring medical interventions, n (%) | 8 (16.7) |
| Pericardial effusion requiring pericardiocentesis due to tamponade, n (%) | 2 (4.9) |
| Mechanical ventilation, n (%) | 17 (35.4) |
| Pulmonary hypertension, n (%) | 1 (2.1) |
| Seizures and posterior reversible encephalopathy syndrome, n (%) | 3 (6.2) |
| Altered mental status, n (%) | 6 (12.5) |
| Intestinal bleeding, n (%) | 5 (10.4) |
| Intestinal stricture, n (%) | 1 (2.1) |
| BSI, n (%) | 26 (54.2) |
| Fungal infection, n (%) | 3 (6.2) |
| BKPyV viremia, n (%) | 19 (43.2) |
| CMV viremia, n (%) | 13 (27.1) |
| EBV viremia, n (%) | 13 (27.1) |
| Adenoviremia, n (%) | 12 (25) |
| Acute GVHD, n (%) | |
| Grade I | 3 (6.5) |
| Grade II | 3 (6.5) |
| Grade III | 4 (8.7) |
| Grade IV | 2 (4.3) |
RRT indicates renal replacement therapy.