Table 5.

Clinical and Laboratory Features Associated with Increased Mortality Risk

Feature	HR (95% CI)	P Value
Univariate analysis
Log sC5b-9	3.02 (1.48–6.15)	.002
ΔsC5b-9 from baseline to TA-TMA diagnosis	1.93 (1.32–2.83)	.001
Maximum rUPCR	1.01 (1.00–1.02)	.068
Number of injured organs	2.40 (1.67–3.35)	.001
Renal replacement therapy	40.75 (8.30–200.10)	<.001
Mechanical ventilation	11.16 (3.57–34.83)	<.001
Seizures	4.13 (1.17–14.53)	.027
Mental status changes	3.81 (1.32–11.00)	.013
GI bleeding	2.79 (0.90–8.63)	.740
Multivariate analysis
Log sC5b-9	2.70 (1.23–5.90)	.013
Maximum rUPCR	1.00 (0.99–1.02)	.485