Table 1.
Risk factors for HCC-related death on univariate and multivariate Cox regression analysis.
| Variable | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | p | HR | 95%CI | p | |
| Age | 1.02 | 0.95–1.10 | 0.542 | |||
| Gender | 1.43 | 0.30–6.74 | 0.650 | |||
| Etiology | 0.71 | 0.35–1.47 | 0.358 | |||
| Pre LT RAF | 0.33 | 0.04–2.55 | 0.285 | |||
| Pre LT TACE | 1.36 | 0.40–4.67 | 0.625 | |||
| MELD | 1.02 | 0.96–1.09 | 0.512 | |||
| BMI (kg/m2) | 1.14 | 0.97–1.34 | 0.116 | |||
| AFP >1000 ng/ml | 8.36 | 1.77–39.46 | 0.007 | 6.63 | 1.31–33.52 | 0.022 |
| Tumor number | 1.99 | 1.09–3.64 | 0.026 | 2.17 | 1.12–4.24 | 0.023 |
| Max tumor diameter (cm) | 1.32 | 1.12–1.56 | 0.001 | 1.33 | 1.08–1.62 | 0.006 |
| Sum of tumor diameter (cm) | 1.21 | 1.07–1.38 | 0.004 | 0.74 | 0.43–1.27 | 0.277 |
| Microvascular invasion | 3.67 | 0.77–17.42 | 0.102 | |||
| TNM Stage | 2.03 | 1.20–3.41 | 0.008 | 1.44 | 0.66–3.15 | 0.362 |
LT, liver transplantation; RAF, radiofrequency ablation; TACE, transhepatic arterial chemotherapy and embolization; MELD, model for end-stage liver disease; BMI, body mass index; AFP, alpha-fetoprotein. Univariate and multivariate analyses were performed based on the Cox proportional hazards regression model. Clinical variables with a P of < 0.1 in the univariate analysis were included in the multivariate analysis.