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. Author manuscript; available in PMC: 2022 Aug 4.
Published in final edited form as: J Trauma Acute Care Surg. 2017 Sep;83(3):406–412. doi: 10.1097/TA.0000000000001590

Figure 4.

Figure 4.

(A) Representative immunohistochemistry images of coronal brain sections demonstrating PMNs in the contusional/pericontusional regions as 1A8-positive cells indicated by black arrows (scale bar 200 μm). (B) Mean PMN counts were quantified by a blinded observer using annotated whole-brain sections in the coronal plane at the level of the contusion (scale bar 3 mm). (C) Compared with untreated injured animals, both UFH treatment groups demonstrated significantly less accumulation of PMNs in penumbral brain tissue. *p < 0.05, **p < 0.01 versus CCI.