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. 2022 Aug 4;17(8):e0272515. doi: 10.1371/journal.pone.0272515

Table 2. Sensitivity, specificity, PPV and NPV of the FPG and HBA1C tests in the diagnosis of diabetes and AGR at the OGTT cut-offs recommended by ADA and WHO.

Test Sensitivity, % Specificity, % PPV NPV
(95% CI) (95% CI)
Diabetes FPG 62.6 (41.5–79.8) 99.4 (98.9–99.7) 0.91 0.97
HBA 1C 69.8 (46.3, 86.1) 98.6 (95.4–99.6) 0.82 0.97
AGR Based on ADA criteria Based on WHO criteria Based on ADA criteria Based on WHO criteria Based on ADA criteria Based on WHO criteria Based on ADA criteria Based on WHO criteria
FPG 47.7 (37.3–58.4) 29.0 (22.5–36.6) 93.5 (88.6–96.4) 98.3 (97.4–98.9) 0.74 0.87 0.82 0.78
HBA 1C 58.9 (46.7–70.2) NA 70.7 (65.1–75.8) NA 0.45 NA 0.82 NA