Table 3. Inhibitory Effects of Compounds 1–6 against LPS-Induced NO Production in RAW264.7 Cells and Their Cytotoxicity^a.

compound	IC50 (μM)b	CC50 (μM)c
1	12.4 ± 0.9	76.7 ± 1.0
2	>100	>100
3	>100	>100
4	11.8 ± 1.2	66.9 ± 3.1
5	29.4 ± 0.2	89.1 ± 2.6
6	41.7 ± 0.7	54.8 ± 4.6

^aAminoguanidine was used as the positive control (IC₅₀ = 15.9 ± 1.7 μM). Results are expressed as the mean IC₅₀ values in μM from triplicate experiments.

^bIC₅₀: 50% inhibitory concentration.

^cCC₅₀: 50% cytotoxic concentration.