Table 3. Binding Constants and Quenching Constants for Ru–Pt Complexes (C1, C2, and C3) with CT-DNA.
complex | UV titration | fluorescence EtBr exchange titration |
||||
---|---|---|---|---|---|---|
Kb × 10–5, M–1 | Ksv × 10–4, M–1 | Kapp × 10–6, M–1 | kq × 10–12, M–1 s–1 | KF × 10–4, M–1 | n | |
C1 | 1.30 ± 0.11 | 1.59 ± 0.07 | 3.33 ± 0.11 | 0.69 ± 0.19 | 1.00 ± 0.05 | 0.99 ± 0.04 |
C2 | 7.68 ± 0.16 | 2.83 ± 0.13 | 6.25 ± 0.17 | 1.23 ± 0.24 | 1.98 ± 0.11 | 0.99 ± 0.05 |
C3 | 14.0 ± 0.23 | 3.92 ± 0.19 | 8.00 ± 0.23 | 1.70 ± 0.31 | 3.96 ± 0.17 | 1.00 ± 0.07 |