Figure 4.

Disrupted microbiota profiles are associated with altered monocyte gene expression pathways following CAP hospitalization

Functional gene set enrichment analysis pathway analysis identified several immune response pathways which were significantly enriched in monocytes of patients with undisrupted microbiota profiles (n = 27; top) and pathways enriched in monocytes of patients with disrupted microbiota profiles (n = 26; bottom). To increase interpretability, collapsed functional pathways with Benjamini-Hochberg adjusted p values <0.05 are shown. All significantly altered pathways are depicted in Figure S6.