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. 2022 Aug 4;19(8):1004–1012. doi: 10.1038/s41592-022-01549-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — (A) Time courses of MB count for a pixel in an arteriole (top, γ in D) and smaller blood vessel (bottom,1^st order branching after descending arteriole, ε in D), illustrated in D. The red shaded intervals correspond to stimulation periods. (B) Time courses of MB count for the same pixels after spatial registration. (C) Time courses of MB flux for the same pixels after pattern summation. (D) Position of pixel γ and ε on a functional correlation map. (E) Time courses of MB count after spatial registration averaged over three different vascular compartments (pial vessels, penetrating vessels and 1st order branching capillaries). (F) Time courses of MB flux averaged over the same three vascular compartments as in (E), after pattern summation. (A-F) N = 7 experiments.