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. 2022 Jun 24;96(10):2815–2824. doi: 10.1007/s00204-022-03327-w

Table 2.

Benchmark doses (BMDs) for 10% benchmark responses (BMRs) with 95% confidence intervals (BMDL–BMDH) (μM) derived considering exposure stage as covariate

Exposure window Exposure NF stages BMD BMDL BMDH
Classical FETAX exposure 8–46 4.48 3.56 5.4
Gastrula 8–13 1244.95 31.5 Inf
Neurula 13–17 15.21 13.6 16.9
Early morphogenesis 13–26 5.18 4.07 5.83
Late morphogenesis 26–38 4.06 3.62 4.67
Tadpole 38–46 27.91 19.6 30.7