Table 5.
Benchmark doses (BMDs) for 10% benchmark responses (BMRs) with 95% Confidence Intervals (BMDL– BMDH) (μM) calculated on data obtained by different method on late morphogenesis exposed group (sensible subgroup)
| Exposure window | BMD | BMDL | BMDH |
|---|---|---|---|
| Gross morphological evaluation | 17.34 | 9.69 | inf |
| Deglutition test | 5.52 | 2.92 | 6.89 |
| Cartilage full evaluation | 4.12 | 3.29 | 5.08 |
| Cartilage whole mount evaluation | 31.83 | 19.1 | inf |
| M–PQ angle | 21.7 | 17.5 | 22.5 |