Table 3.
Univariable and multivariable Cox proportional hazards model for disease-free survival (n = 310).
| Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | |
| Age, continuous | 0.99 (0.96–1.02) | 0.62 | 0.98 (0.96–1.01) | 0.26 |
| Sex | ||||
| Male | Reference | Reference | ||
| Female | 1.84 (0.87–3.91) | 0.11 | 1.64 (0.76–3.53) | 0.21 |
| Histology† | ||||
| Lymphoepithelial / undifferentiated / NOS carcinoma | 0.72 (0.27–1.88) | 0.51 | 0.84 (0.31–2.28) | 0.74 |
| Squamous cell carcinoma, non-keratinizing | Reference | Reference | ||
| Clinical T classification | ||||
| T1 | Reference | Reference | ||
| T2 | 1.75 (0.72–4.29) | 0.22 | 1.73 (0.70–4.27) | 0.24 |
| T3 | 1.13 (0.44–2.86) | 0.80 | 1.25 (0.49–3.21) | 0.64 |
| T4 | 0.69 (0.22–2.13) | 0.52 | 0.66 (0.21–2.06) | 0.47 |
| Clinical N classification | ||||
| N3a | Reference | Reference | ||
| N3b | 1.04 (0.49–2.20) | 0.93 | 1.04 (0.48–2.28) | 0.92 |
| Adjuvant treatment | ||||
| Observation | Reference | Reference | ||
| Adjuvant PF chemotherapy | 0.25 (0.10–0.67) | 0.005 | 0.24 (0.09–0.63) | 0.004 |
CI, confidence interval; NOS, not otherwise specified.
†There were no events for the Squamous cell carcinoma, keratinizing or NOS group.