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. 2022 Aug 4;5:785. doi: 10.1038/s42003-022-03767-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Schematic of filovirus GP domain structure with annotated N-linked glycosylation and C-mannosylation. The cladogram on the left is based on the full GP sequences. Domain coloring as indicated below the diagram. Conserved N-linked glycans in ebolavirus species are annotated on top. b Pseudomodel of EBOV GP with core pentasaccharide of N-linked glycans shown as orange spheres. Model is built with GLYCAM based on PDB ID 5JQ3. The yellow lines indicate the approximate location of the MLD, connecting the respective termini of the glycan cap and GP2 subunits.