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. 2022 Aug 4;8:351. doi: 10.1038/s41420-022-01145-8

Table 1.

Univariate and multivariate analyses of risk score and patient overall survival.

Variables Univariate analysis Multivariate analysisc
HRa 95% CIb P value HRa 95% CIb P value
Age (years) <60 vs ≥60 1.766 1.297–2.404 <0.001 1.680 1.232–2.293 0.001
Gender Female vs Male 0.965 0.707–1.318 0.825
T stage T1 or T2 vs T3 or T4 3.043 2.245–4.124 <0.001 1.528 1.062–2.197 0.022
N stage N0 or Nx vs N1 3.554 1.871–6.748 <0.001 1.864 0.968–3.591 0.063
M stage M0 or Mx vs M1 4.369 3.197–5.971 <0.001 2.505 1.739–3.609 <0.001
Grade G1 or G2 or Gx vs G3 or G4 2.605 1.853–3.661 <0.001 1.559 1.078–2.256 0.018
SLC27A2 High vs Low 0.350 0.252–0.486 <0.001 0.520 0.367–0.738 <0.001

aHazard ratio, estimated from Cox proportional hazard regression model.

bConfidence interval of the estimated HR.

cMultivariate models were adjusted for T, N, M classification, age, and gender.