Table 2.
Repeatability and accuracy of the quantitative determination of 14 active pharmaceutical ingredients with the TLCyzer app. The results of all 168 individual measurements are displayed graphically in Fig. 3, and their numerical values are listed in Supplementary Table S2.
API | Conc. (%) | Mean (%) (n = 4) | SD (%) (n = 4) | Relative SD [%] (n = 4) | Relative SD [%] (n = 12) | Recovery mean (n = 4) [%] |
---|---|---|---|---|---|---|
Atenolol | 70 | 72.5 | 0.59 | 0.81 | 2.33 | 103.5 |
85 | 85.9 | 1.59 | 1.85 | 101.1 | ||
90 | 91.7 | 3.97 | 4.33 | 101.8 | ||
Ceftriaxone | 70 | 70.1 | 3.99 | 5.68 | 3.50 | 100.2 |
85 | 84.1 | 1.00 | 1.18 | 99.8 | ||
90 | 90.4 | 3.31 | 3.63 | 101.3 | ||
Cefuroxime axetil | 70 | 72.0 | 3.09 | 4.29 | 3.70 | 102.9 |
85 | 82.3 | 2.13 | 2.59 | 96.8 | ||
90 | 90.5 | 3.82 | 4.23 | 100.5 | ||
Chloroquine | 70 | 68.7 | 0.93 | 1.36 | 1.59 | 98.1 |
85 | 85.5 | 0.95 | 1.11 | 100.5 | ||
90 | 91.9 | 2.11 | 2.30 | 102.1 | ||
Ciprofloxacin | 70 | 69.8 | 1.93 | 2.77 | 3.34 | 99.7 |
85 | 84.7 | 3.53 | 4.17 | 99.6 | ||
90 | 92.5 | 2.86 | 3.09 | 102.8 | ||
Dexamethasone | 70 | 67.5 | 2.75 | 4.08 | 2.92 | 96.4 |
85 | 85.2 | 2.07 | 2.43 | 100.3 | ||
90 | 92.1 | 2.08 | 2.26 | 102.3 | ||
Fluconazole | 70 | 70.4 | 1.68 | 2.39 | 2.40 | 100.6 |
85 | 84.3 | 1.54 | 1.82 | 99.1 | ||
90 | 89.1 | 2.68 | 3.01 | 99.0 | ||
Furosemide | 70 | 70.3 | 1.82 | 2.59 | 2.28 | 100.5 |
85 | 85.1 | 2.20 | 2.58 | 100.1 | ||
90 | 92.6 | 1.54 | 1.66 | 102.8 | ||
Glibenclamide | 70 | 68.5 | 2.04 | 2.98 | 3.17 | 97.9 |
85 | 83.0 | 4.34 | 5.23 | 97.6 | ||
90 | 90.6 | 1.17 | 1.29 | 100.6 | ||
Hydrochloro-thiazide | 70 | 70.8 | 1.27 | 1.80 | 1.98 | 101.2 |
85 | 85.5 | 1.24 | 1.45 | 100.6 | ||
90 | 90.9 | 2.46 | 2.70 | 101.0 | ||
Metformin | 70 | 72.0 | 3.45 | 4.80 | 3.21 | 102.8 |
85 | 83.7 | 1.94 | 2.32 | 98.5 | ||
90 | 89.1 | 2.25 | 2.53 | 99.0 | ||
Metronidazole | 70 | 69.2 | 2.38 | 3.44 | 2.33 | 98.8 |
85 | 85.0 | 0.66 | 0.77 | 100.0 | ||
90 | 90.0 | 2.50 | 2.77 | 100.0 | ||
Sulfamethoxazole | 70 | 70.1 | 3.38 | 4.82 | 3.84 | 100.2 |
85 | 87.4 | 2.91 | 3.33 | 102.8 | ||
90 | 93.5 | 3.17 | 3.39 | 103.9 | ||
Trimethoprim | 70 | 68.6 | 1.53 | 2.22 | 2.48 | 98.0 |
85 | 84.0 | 2.86 | 3.41 | 98.8 | ||
90 | 88.2 | 1.61 | 1.82 | 97.9 | ||
Mean | 2.79 | 100.3 |