Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Structures of CRISPR-Cas9 at different states. a Domains of the Cas9-sgRNA-DNA ternary complex are marked by different colors. Cas9 contains 1368 amino acids. b The structures are determined by X-ray diffraction or Cryo-electron microscopy, including Cas9 monomer (PDB ID: 4CMP), Cas9-sgRNA binary complex (PDB ID: 4ZT0), and Cas9-sgRNA-DNA ternary complexes (PDB IDs: 4OO8, 4UN3, 5F9R, 5Y36)
