. 2022 Aug 4;5:109. doi: 10.1038/s41746-022-00638-1

Table 6.

Diagnostic and predictive models built using mixed variables.

AI methods used	Authors [ref.]	Stage of endometriosis	Type of endometriosis	Sample size	Inputs used	Evaluation Metric
Logistic Regression	Guo et al.⁵⁸	All stages of endometriosis and stage 3/4 endometriosis	NR	1016 infertile patients	for any-stage endometriosis nomogram: BMI, Cycle length, parity, palpable nodularity, endometrioma diagnosed on TVS, tubal pathology; for stage 3–4 endometriosis nomogram: pain, palpable nodularity, endometrioma diagnosed on TVS	SE = NR SP = NR
Logistic Regression	Chattot et al.⁵⁷	Not specified	NR	119 patients (47 endometriosis with rectosigmoid involvement, 72 endometriosis without rectosigmoid involvement)	Palpation of a posterior nodule on digital examination, UBESS score of 3 on ultrasonography, rectosigmoid involvement in endometriosis infiltration on MRI, presence of blood in the stools during menstruation	SE = NR SP = NR
Logistic Regression	Nnoaham et al.²⁷	Stage 3 and 4 endometriosis	NR	1396 symptomatic women	Ultrasound evidence, menstrual dyschezia, ethnicity, history of benign ovarian cysts	SE = 82.6% SP = 75.8%

AI methods used

Authors [ref.]

Stage of endometriosis

Type of endometriosis

Sample size

Inputs used

Evaluation
Metric

Logistic Regression

Guo et al.⁵⁸

All stages of endometriosis and stage 3/4 endometriosis

1016 infertile patients

for any-stage endometriosis nomogram: BMI, Cycle length, parity, palpable nodularity, endometrioma diagnosed on TVS, tubal pathology; for stage 3–4 endometriosis nomogram: pain, palpable nodularity, endometrioma diagnosed on TVS

SE = NR

SP = NR

Logistic Regression

Chattot et al.⁵⁷

Not specified

119 patients (47 endometriosis with rectosigmoid involvement, 72 endometriosis without rectosigmoid involvement)

Palpation of a posterior nodule on digital examination, UBESS score of 3 on ultrasonography, rectosigmoid involvement in endometriosis infiltration on MRI, presence of blood in the stools during menstruation

SE = NR

SP = NR

Logistic Regression

Nnoaham et al.²⁷

Stage 3 and 4 endometriosis

1396 symptomatic women

Ultrasound evidence, menstrual dyschezia, ethnicity, history of benign ovarian cysts

SE = 82.6%

SP = 75.8%

NR not reported, BMI body mass index, TVS transvaginal ultrasound, UBESS ultrasound-based endometriosis staging system, MRI magnetic resonance imaging, SE sensitivity, SP specificity.