Table 2.

DEGs (Differentially Expressed Genes) in the CRC dataset. The genes that exhibited adjusted p-value of ≤ 0.05 and Log2 Fold Change (LFC) ≥ 2 (two) were considered as DEG in the CRC dataset. DEGs that are also present in the list of salient genes are denoted by (*).

Genes	LFC	Average expression	t value	p-value	FDR adjusted p-value	B value
GCG	− 2.38358	4.969389	− 15.752	6.92E−52	1.29E−48	107.0804
FOXQ1	2.41793	9.809112	15.58703	6.45E−51	9.47E−48	104.8698
CA1	− 2.68165	7.905425	− 15.5739	7.71E−51	1.06E−47	104.6939
CEMIP	2.019388	8.943608	15.43317	5.10E−50	6.17E−47	102.8227
CLDN8	− 2.37615	4.975604	− 14.9159	4.78E−47	3.39E−44	96.04866
AQP8	− 2.20027	6.339491	− 14.6653	1.24E−45	6.68E−43	92.8299
SLC4A4	− 2.69512	6.884806	− 14.5002	1.03E−44	4.82E−42	90.73028
PKIB	− 2.09604	7.226978	− 13.9028	1.91E−41	5.58E−39	83.28646
MT1M*	− 2.12435	6.256335	− 13.8111	5.93E−41	1.54E−38	82.16609
MS4A12	− 2.71223	6.861364	− 13.7431	1.37E−40	3.35E−38	81.33784
ZG16	− 2.74676	8.079408	− 13.6444	4.59E−40	1.03E−37	80.14146
CLCA4	− 3.05432	6.704506	− 13.5764	1.05E−39	2.14E−37	79.32192
CA2	− 2.43465	8.684428	− 12.687	3.99E−35	4.53E−33	68.89684
ADH1C	− 2.11602	7.314942	− 11.9071	2.59E−31	1.71E−29	60.22568
SI*	− 2.37608	6.102779	− 11.4662	3.02E−29	1.51E−27	55.52607
PCK1	− 2.02539	8.368289	− 11.4555	3.38E−29	1.69E−27	55.41363
MMP3	2.000444	8.471801	11.2982	1.78E−28	8.17E−27	53.77398
MMP1	2.123265	8.813216	10.83644	2.09E−26	7.03E−25	49.07185
KRT23	2.006019	7.476861	10.55127	3.65E−25	1.08E−23	46.25175
HEPACAM2	− 2.06678	6.938537	− 10.292	4.65E−24	1.23E−22	43.74442
CEACAM7	− 2.10091	9.917928	− 10.0767	3.69E−23	8.83E−22	41.70331
SLC26A3	− 2.45108	9.32326	− 9.64708	2.06E−21	3.95E−20	37.74335
ITLN1	− 2.20724	7.95737	− 9.6134	2.80E−21	5.29E−20	37.43937
CLCA1	− 2.07261	8.930104	− 8.52471	3.65E−17	4.48E−16	28.12584