Table 2.
Patient Symptoms by Vitamin B12a
| Total (N=2142) | B12<400 ng/L (N=908) | B12≥400 ng/L (N=1234) | P value | B12<350 ng/L (N=724) | B12≥350 ng/L (N=1418) | P value | |
|---|---|---|---|---|---|---|---|
| Fatigue | .01 | .017 | |||||
| N | 1777 (83.0%) | 731 (80.5%) | 1046 (84.8%) | 581 (80.2%) | 1196 (84.3%) | ||
| Y | 365 (17.0%) | 177 (19.5%) | 188 (15.2%) | 143 (19.8%) | 222 (15.7%) | ||
| Confusion | .48 | .71 | |||||
| N | 2138 (99.8%) | 907 (99.9%) | 1231 (99.8%) | 723 (99.9%) | 1415 (99.8%) | ||
| Y | 4 (0.2%) | 1 (0.1%) | 3 (0.2%) | 1 (0.1%) | 3 (0.2%) | ||
| Memory loss | .058 | .09 | |||||
| N | 2041 (95.3%) | 856 (94.3%) | 1185 (96.0%) | 682 (94.2%) | 1359 (95.8%) | ||
| Y | 101 (4.7%) | 52 (5.7%) | 49 (4.0%) | 42 (5.8%) | 59 (4.2%) | ||
| Brain fog | .19 | .34 | |||||
| N | 2037 (95.1%) | 857 (94.4%) | 1180 (95.6%) | 684 (94.5%) | 1353 (95.4%) | ||
| Y | 105 (4.9%) | 51 (5.6%) | 54 (4.4%) | 40 (5.5%) | 65 (4.6%) | ||
| Cognitive impairment | .18 | .08 | |||||
| N | 2081 (97.2%) | 877 (96.6%) | 1204 (97.6%) | 697 (96.3%) | 1384 (97.6%) | ||
| Y | 61 (2.8%) | 31 (3.4%) | 30 (2.4%) | 27 (3.7%) | 34 (2.4%) | ||
| Paresthesia | .44 | .21 | |||||
| N | 2029 (94.7%) | 864 (95.2%) | 1165 (94.4%) | 692 (95.6%) | 1337 (94.3%) | ||
| Y | 113 (5.3%) | 44 (4.8%) | 69 (5.6%) | 32 (4.4%) | 81 (5.7%) | ||
| Tingling | .26 | .34 | |||||
| N | 2103 (98.2%) | 888 (97.8%) | 1215 (98.5%) | 708 (97.8%) | 1395 (98.4%) | ||
| Y | 39 (1.8%) | 20 (2.2%) | 19 (1.5%) | 16 (2.2%) | 23 (1.6%) | ||
| Numbness | .4 | .53 | |||||
| N | 2061 (96.2%) | 870 (95.8%) | 1191 (96.5%) | 694 (95.9%) | 1367 (96.4%) | ||
| Y | 81 (3.8%) | 38 (4.2%) | 43 (3.5%) | 30 (4.1%) | 51 (3.6%) | ||
| Neuropathy | .57 | .24 | |||||
| N | 2040 (95.2%) | 862 (94.9%) | 1178 (95.5%) | 684 (94.5%) | 1356 (95.6%) | ||
| Y | 102 (4.8%) | 46 (5.1%) | 56 (4.5%) | 40 (5.5%) | 62 (4.4%) |
a
B12 = vitamin B12; N = no; Y = yes.