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. 2022 Jul 22;13:899124. doi: 10.3389/fgene.2022.899124

TABLE 4.

Association between SLC11A1 polymorphisms and the TB risk stratified by gender.

SNP-ID Model Genotype Male Female
OR (95% CI) P OR (95% CI) P
rs7608307 Co-dominant CC 1 1
CT 1.69 (1.12–2.56) 0.013 0.75 (0.46–1.23) 0.255
TT 0.79 (0.17–3.56) 0.753
Dominant CC 1 1
CT-TT 1.61 (1.08–2.41) 0.020 0.73 (0.45–1.20) 0.219
Recessive CC-CT 1 1
TT 0.72 (0.16–3.24) 0.666
Log-additive -- 1.47 (1.01–2.13) 0.043 0.72 (0.44–1.17) 0.185
rs4674301 Co-dominant TT 1 1
TC 0.89 (0.63–1.26) 0.508 0.98 (0.63–1.51) 0.921
CC 0.77 (0.36–1.63) 0.490 3.82 (1.04–4.03) 0.043
Dominant TT 1
TC-CC 0.87 (0.63–1.21) 0.414 1.11 (0.73–1.69) 0.626
Recessive TT-TC 1
CC 0.79 (0.37–1.68) 0.546 3.85 (1.06–4.02) 0.041
Log-additive -- 0.88 (0.67–1.16) 0.371 1.24 (0.86–1.78) 0.249
rs13062 Co-dominant CC 1 1
CA 1.52 (1.10–2.12) 0.012 0.98 (0.64–1.49) 0.914
AA 0.76 (0.42–1.36) 0.352 0.64 (0.29–1.41) 0.269
Dominant CC 1 1
CA-AA 0.79 (0.37–1.68) 0.546 0.91 (0.61–1.37) 0.663
Recessive CC-CA 1 1
AA 0.63 (0.36–1.10) 0.104 0.65 (0.30–1.39) 0.267
Log-additive -- 1.10 (0.86–1.40) 0.453 0.88 (0.64–1.20) 0.414

CI: confidence interval; OR: odds ratio; SNP: single-nucleotide polymorphism; TB: tuberculosis. p < 0.05 indicates statistical significance.