TABLE 5.
Association between SLC11A1 polymorphisms and the TB risk stratified by age.
| SNP-ID | Model | Genotype | ≤41 | >41 | ||
|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |||
| rs7608307 | Co-dominant | CC | 1 | 1 | ||
| CT | 1.66 (1.04–2.65) | 0.035 | 0.99 (0.63–1.57) | 0.972 | ||
| TT | 0.34 (0.06–1.99) | 0.232 | — | — | ||
| Dominant | CC | 1 | 1 | |||
| CT-TT | 1.50 (0.95–2.36) | 0.080 | 1.01 (0.64–1.60) | 0.970 | ||
| Recessive | CC-CT | 1 | 1 | |||
| TT | 0.32 (0.05–1.83) | 0.198 | — | — | ||
| Log-additive | -- | 1.30 (0.86–1.97) | 0.209 | 1.03 (0.66–1.62) | 0.902 | |
| rs13062 | Co-dominant | CC | 1 | 1 | ||
| CA | 1.19 (0.82–1.72) | 0.362 | 1.25 (0.85–1.86) | 0.260 | ||
| AA | 0.96 (0.51–1.80) | 0.892 | 0.44 (0.20–0.98) | 0.043 | ||
| Dominant | CC | 1 | 1 | |||
| CA-AA | 1.14 (0.80–1.63) | 0.458 | 1.08 (0.74–1.56) | 0.703 | ||
| Recessive | CC-CA | 1 | 1 | |||
| AA | 0.88 (0.48–1.63) | 0.692 | 0.40 (0.18–0.87) | 0.021 | ||
| Log-additive | -- | 1.06 (0.81–1.38) | 0.694 | 0.90 (0.67–1.22) | 0.498 | |
CI: confidence interval; OR: odds ratio; SNP: single-nucleotide polymorphism; TB: tuberculosis. *p < 0.05 indicates statistical significance.