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. 2022 Jul 22;13:963070. doi: 10.3389/fendo.2022.963070

Table 4.

Infulential factors of PTH restoration in patients underwent TTIPA - Multivatirate and Univariate Cox model.

Variables Univariable Analysis Multivariable Analysis
HR (95% CI) P-value HR (95% CI) P-value
Age 1.01 (1.00-1.02) 0.049 1.01 (1.00-1.02) 0.056
PTG autotransplantation with same side CLND (Yes =1, No= 0) 0.56 (0.38-0.82) 0.003 0.56 (0.38-0.82) 0.003
Method of thyroidectom (Endoscopic =1, Open =0) 1.57 (1.06-2.32) 0.023 1.54 (1.04-2.28) 0.029
BMI 1.00 (0.97-1.03) 0.910
Duration of operation 1.00 (1.00-1.00) 0.640
Serum glucose in POD1 1.00 (0.93-1.09) 0.932
Intraoperative blood loss 1.00 (1.00-1.00) 0.600
Post-operative drainag 1.00 (1.00-1.00) 0.920
Preoperative serum glucose 1.01 (0.89-1.15) 0.882
Average hospitalization time 0.99 (0.93-1.06) 0.807
Number of PTG autotransplantation 0.92 (0.79-1.06) 0.233
FNA (Yes =1, No = 0) 0.98 (0.79-1.22) 0.887
Gender (Female =1, Male =0) 1.21 (0.90-1.63) 0.203
Hashimoto thyroiditis (Yes =1, No= 0) 1.05 (0.83-1.32) 0.692
BRAF V600E mutation status (Mutation =1, Wild type = 0) 0.99 (0.88-1.12) 0.895
Lateral lymph node dissection (Yes =1, No =0) 1.00 (1.00-1.00) 0.854
Central lymph node dissection (Unilateral= 1, Bilateral= 0) 1.09 (0.95-1.24) 0.209
Lymph node metastisis, pathology (Yes =1, No =0) 1.00 (0.81-1.24) 0.963

PTH, Parathyroid hormone; TTIPA, Total thyroidectomy with intraoperative parathyroid autotransplantation; PTG, Parathyroid gland; CLND, Central lymph node dissection; BMI, Body Mass Index; POD number, Post-operative day number; FNA, Fine needle aspiration.