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. 2022 Jun 7;84(7):1023–1028. doi: 10.1292/jvms.21-0617

Table 2. Sensitivities of Klebsiella pneumoniae and Escherichia coli isolates to various antibiotics.

Year 2004–2008
2009–2014
Antibiotic therapy Cefazolin throughout treatment period
Cefazolin throughout treatment period
Cefazolin replaced with a fluoroquinolone on day 2
Causative agent K. pneumoniae E. coli K. pneumoniae E. coli K. pneumoniae E. coli
(n=53) (n=50) (n=60) (n=118) (n=30) (n=10)
PC 0/47 (0%)* 0/47 (0%) 0/58 (0%) 0/92 (0%) 0/30 (0%) 0/9 (0%)
ABPC 6/46 (13.0%) 36/47 (76.6%) 3/58 (5.2%) 56/88 (63.6%) 2/28 (7.1%) 3/9 (33.3%)
CEZ 42/47 (89.4%) 45/47 (95.7%) 48/58 (82.8%) 115/115 (100%) 22/30 (73.3%) 7/10 (70.0%)
OTC 34/46 (73.9%) 34/47 (72.3%) 41/58 (70.7%) 81/96 (84.4%) 21/30 (70.0%) 3/9 (33.3%)
KM 46/47 (97.9%) 38/47 (80.9%) 52/58 (89.7%) 91/97 (93.8%) 20/30 (66.7%) 9/10 (90.0%)
OBFX 11/11 (100%) 3/3 (100%) 44/44 (100%) 88/88 (100%) 25/25 (100%) 8/8 (100%)
ERFX Not tested 1/1 (100%) 17/17 (100%) 31/31 (100%) 6/6 (100%) 4/4 (100%)

*: Number of susceptible isolates. PC: penicillin, ABPC: ampicillin, CEZ: cefazolin, OTC: oxytetracycline, KM: kanamycin, OBFX: orbifloxacin and ERFX: enrofloxacin. Data are given as the number of susceptible isolates / the total number of isolates tested (percentage).