Table 2. Sensitivities of Klebsiella pneumoniae and Escherichia coli isolates to various antibiotics.
Year | 2004–2008 |
2009–2014 |
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---|---|---|---|---|---|---|
Antibiotic therapy | Cefazolin throughout treatment period |
Cefazolin throughout treatment period |
Cefazolin replaced with a fluoroquinolone on day 2 |
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Causative agent | K. pneumoniae | E. coli | K. pneumoniae | E. coli | K. pneumoniae | E. coli |
(n=53) | (n=50) | (n=60) | (n=118) | (n=30) | (n=10) | |
PC | 0/47 (0%)* | 0/47 (0%) | 0/58 (0%) | 0/92 (0%) | 0/30 (0%) | 0/9 (0%) |
ABPC | 6/46 (13.0%) | 36/47 (76.6%) | 3/58 (5.2%) | 56/88 (63.6%) | 2/28 (7.1%) | 3/9 (33.3%) |
CEZ | 42/47 (89.4%) | 45/47 (95.7%) | 48/58 (82.8%) | 115/115 (100%) | 22/30 (73.3%) | 7/10 (70.0%) |
OTC | 34/46 (73.9%) | 34/47 (72.3%) | 41/58 (70.7%) | 81/96 (84.4%) | 21/30 (70.0%) | 3/9 (33.3%) |
KM | 46/47 (97.9%) | 38/47 (80.9%) | 52/58 (89.7%) | 91/97 (93.8%) | 20/30 (66.7%) | 9/10 (90.0%) |
OBFX | 11/11 (100%) | 3/3 (100%) | 44/44 (100%) | 88/88 (100%) | 25/25 (100%) | 8/8 (100%) |
ERFX | Not tested | 1/1 (100%) | 17/17 (100%) | 31/31 (100%) | 6/6 (100%) | 4/4 (100%) |
*: Number of susceptible isolates. PC: penicillin, ABPC: ampicillin, CEZ: cefazolin, OTC: oxytetracycline, KM: kanamycin, OBFX: orbifloxacin and ERFX: enrofloxacin. Data are given as the number of susceptible isolates / the total number of isolates tested (percentage).