Table 3. Comparison of clinical cure rate of an acute mastitis caused by Klebsiella pneumoniae and Escherichia coli.

Year	2004–2008		2009–2014
Antibiotic therapy	Cefazolin throughout treatment period		Cefazolin throughout treatment period		Cefazolin replaced with a fluoroquinolone on day 2
Causative agent	K. pneumoniae	E. coli	K. pneumoniae	E. coli	K. pneumoniae	E. coli
Cows	53	50	60	118	30	10
Cure	28	43	41	108	23	8
Death or culling	25	7	19	10	7	2
Cure rate	52.8%a	86.0%b	68.3%c	91.5%d	76.7%e	80.0%f

Statistical analysis showed that neither a and c (P=0.248), b and d (P=0.363), c and d (P=0.197), nor a and e (P=0.843) differed significantly from each other.