Table III.
Univariate and multivariate analysis.
| Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
|
|
|
|||
| Laboratory and clinicopathological factors | HR (95% CI) | P-value | HR (95% CI) | P-value |
| Leukocyte >6.63 vs. ≤6.63×109/l | 2.05 (1.02-4.10) | 0.043 | 3.14 (1.38-7.72) | 0.007 |
| Lymphocyte >1.79 vs. ≤1.79×109/l | 2.10 (1.02-4.31) | 0.043 | - | - |
| Neutrophils >4.32 vs. ≤4.32×109/l | 2.35 (1.20-4.63) | 0.013 | - | - |
| Monocyte >0.58 vs. ≤0.58×109/l | 1.60 (0.80-3.21) | 0.183 | - | - |
| Platelets >299 vs. ≤299×109/l | 3.40 (1.47-7.85) | 0.004 | - | - |
| Hemoglobin >14.2 vs. ≤14.2 g/dl | 0.55 (0.26-1.15) | 0.114 | - | - |
| RBC >4.51 vs. ≤4.51×1012/l | 0.54 (0.27-1.08) | 0.083 | 0.40 (0.17-0.92) | 0.031 |
| NLR >4.66 vs. ≤4.66 | 4.25 (1.49-12.11) | 0.007 | 10.83 (2.79-42.0) | 0.001 |
| PLR >89.6 vs. ≤89.6 | 1.64 (0.63-4.24) | 0.308 | 2.72 (0.90-8.29) | 0.078 |
| LMR >3.26 vs. ≤3.26 | 1.76 (0.88-3.52) | 0.109 | 3.14 (1.38-7.17) | 0.007 |
| Gleason score >7 vs. ≤7 | 2.94 (1.39-6.21) | 0.005 | 2.70 (1.14-6.39) | 0.024 |
| PSA >20 vs. ≤20 ng/ml | 3.88 (1.93-7.78) | 0.0001 | 2.63 (1.25-5.53) | 0.011 |
| Age >70 vs. ≤70 years | 2.31 (1.15-4.64) | 0.018 | 3.66 (1.62-8.30 | 0.002 |
| Smoking Yes vs. No | 3.00 (1.45-6.24) | 0.003 | 3.40 (1.46-7.95) | 0.005 |
| Diabetes | 0.72 (0.10-5.29) | 0.748 | - | - |
| Hypertension | 0.71 (0.36-1.43) | 0.340 | - | - |
| Cardiological diseases | 1.09 (0.47-2.52) | 0.835 | - | - |
| Cancer in family history | 0.92 (0.47-1.83) | 0.818 | 0.47 (0.20-1.11) | 0.087 |
HR, hazard ratio; CI, confidence interval; PLR, platelet-lymphocyte ratio; NLR, neutrophil-lymphocyte ratio; LMR, lymphocyte-monocyte ratio; PLT, platelets; RBC, red blood cells; PSA, prostate-specific antigen.