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. 2022 May 18;9(22):2105144. doi: 10.1002/advs.202105144

Figure 4.

Figure 4

Bio‐fabrication of a functional vascular model in cell‐laden hydrogels. a) 3D model of a construct with a core surrounded by four channels, emulating vasculature. b) Side‐view of how light is blurred as it penetrates into the hydrogel with cells. c) Corresponding light patterns projected at different angles during tomographic VAM with and without correction. The difference shows by where and by how much is the correction applied to account for scattering d) Photographs of the resulting printed constructs after dying them in red. e) Timelapses of a blue dye flowing through the constructs. The scattering corrected tomographic VAM produces an object that matches the geometry and function of the model; while conventional tomographic VAM results in an unintended malfunctioning tube at the center of the construct. f) Fluorescence microscopy image of stained nuclei of cells in the fabricated hydrogels (4.0 million cells mL−1).