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. 2022 Jul 22;13:935286. doi: 10.3389/fgene.2022.935286

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Copyright © 2022 Ullah, Islam, Moin, Park and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mutation analysis report on PSMC genes in LUAD patients presented in OncoPrint diagram (A). The colored region of the column represents different alterations, and the alternation frequency is a fraction of the colored columns over the total columns. Amplification was found to be the most prevalent form of genetic alteration in all PSMC genes across different LUAD studies. The distribution of mutation and CNA in PSMC genes across different LUAD studies is oriented in bar diagram (B). The y-axis represents the percentage of total samples mutated in each LUAD study correspondingly presented in the x-axis. Bubble plot representing the positive correlation between the CNAs present in PSMC genes and their mRNA level expression in LUAD tissues (C).