Table II.
Multiple linear stepwise regression analysis for prediction the independent risk variables of plasma TNF-α.
| TNF-α concentration | ||||||
|---|---|---|---|---|---|---|
| Variable | Unstandardized β | SE (β) | Standardized β | P-value | VIF | 95% CI |
| Constant | -0.028 | 0.015 | - | 0.06 | - | -0.057-0.001 |
| Age | 0.000 | 0.000 | 0.050 | 0.285 | 1.249 | -0.000-0.001 |
| Sex | 0.004 | 0.008 | 0.023 | 0.598 | 1.104 | -0.011-0.019 |
| BMI | -0.001 | 0.001 | 0.911 | 0.548 | 1.505 | -0.003-0.002 |
| NAFLD stage | 0.073 | 0.004 | 0.849 | <0.001 | 1.241 | 0.066-0.081 |
| T2DM | -0.017 | 0.009 | -0.076 | 0.068 | 1.026 | -0.035-0.001 |
| Hypertension | -0.001 | 0.011 | -0.004 | 0.933 | 1.100 | -0.022-0.021 |
| Dyslipidemia | -0.006 | 0.008 | -0.034 | 0.453 | 1.157 | -0.023-0.010 |
| Acetate | -0.000 | 0.000 | -0.108 | 0.156 | 3.328 | -0.000-0.000 |
| Propionate | -0.000 | 0.000 | -0.035 | 0.662 | 3.786 | -0.000-0.000 |
| Butyrate | -0.000 | 0.000 | -0.058 | 0.458 | 3.485 | -0.000-0.000 |
| Total main SCFAs | -0.0001 | 0.000 | -0.189 | <0.001 | 1.212 | -0.000-0.000 |
| Elevated aminotransferases | -0.013 | 0.010 | -0.072 | 0.214 | 1.931 | -0.032-0.007 |
| FIB-4 | -0.000 | 0.006 | -0.003 | 0.965 | 3.397 | -0.013-0.012 |
BMI, body mass index; NAFLD, non-alcoholic fatty liver disease; T2DM, type 2 diabetes mellitus; SCFA, short-chain fatty acid; FIB-4, fibrosis-4; β, regression coefficient; SE, standardized error; VIF, variance inflation factor; CI, confidence interval.