Table 6.

Oxidative stress and inflammatory plasma markers.

Indices	Groups	Before	3 months		6 months
SOD	Treatment	883.50 ± 164.26	717.48 ± 233.11	0.003	689.71 ± 203.60	≤0.001
(u/L)	Placebo	887.04 ± 114.26	844.56 ± 150.04	0.228	807.88 ± 182.10	0.109
	P-value	0.930	0.026		0.036
IL-6 (pg/ml)	Treatment	177.90 ± 52.22	110.80 ± 28.57	≤0.001	58.04 ± 22.06	≤0.001
	Placebo	179.60 ± 54.89	220.50 ± 57.8	≤0.001	194.20 ± 40.14	0.171
	P-value	0.912	≤0.001		≤0.001
IL-10 (pg/ml)	Treatment	63.44 ± 20.24	137.60 ± 55.70	≤0.001	237.90 ± 94.98	≤0.001
	Placebo	64.68 ± 36.82	65.64 ± 40.23	0.905	68. ± 32.92	0.581
	P-value	0.883	≤0.001		≤0.001
NO (μmol/L)	Treatment	85.64 ± 16.90	78.18 ± 22.22	0.049	75.05 ± 26.39	0.043
	Placebo	83.22 ± 18.19	65.58 ± 18.73	≤0.001	55.83 ± 19.37	≤0.001
	P-value	0.630	0.035		0.005
TNF-α (pg/L)	Treatment	261.10 ± 70.55	412.20 ± 152.10	≤0.001	301.80 ± 134.20	0.164
	Placebo	251.00 ± 77.49	698.70 ± 284.50	≤0.001	680.30 ± 199.60	≤0.001
	P-value	0.634	≤0.001		≤0.001

The values in the fifth column mean differences between 3 months after first chemotherapy and before chemotherapy; the values in the seventh column mean differences between 6 months after first chemotherapy and before chemotherapy.