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In vivo activity of alpha mangostin against S. aureus MW2 persisters in the G. mellonella wax moth model. (A–D). Sixteen S. aureus persister infected G. mellonella were treated with control (PBS), 25 mg/kg vancomycin and 2, 4, 8, 16 mg/kg alpha mangostin at 1 h of post infection. Seventy five percentage of larvae survived with treatment of 8 mg/kg of alpha mangostin was significant compared to PBS treatment (p<0.0001).
