表 3 复发/难治多发性骨髓瘤患者BCMA靶向的CAR-T细胞治疗期间发生AKI危险因素的多因素logistic回归分析结果
Table 3 Results of multivariant logistic regression analysis of risk factors associated with the occurrence of AKI in relapsed/refractory multiple myeloma patients during BCMA CAR-T cell therapy
影响因素 |
偏回归系数 |
标准误 |
P值 |
相对危险度 (95% CI) |
预处理后SCr水平 |
0.020 |
0.005 |
<0.001 |
1.020(1.010~1.030) |
3~4级CRS |
1.872 |
0.628 |
<0.01 |
6.501(1.899~22.251) |
BCMA:B细胞成熟抗原;CAR:嵌合抗原受体;AKI:急性肾损伤;SCr:血清肌酐;CRS:细胞因子释放综合征.