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. 2022 Jul 22;10:861916. doi: 10.3389/fcell.2022.861916

FIGURE 5.

FIGURE 5

Intracellular amount of LDs affects the nuclear translocation of NF-κB (p65). (A) NNE cell line NP69 was treated with oleic acid (OA) for 48 h to increase intracellular LDs. The NF-κB (p65) expression in the nuclear fraction from NP69 cells was analyzed using Western blot. (B–C): Transcriptional level of pro-inflammatory cytokines IL6, IL8, IL1α, and CXCL2 was negatively correlated with the intracellular amount of LDs in noncancerous nasopharyngeal epithelial cells and NPC-derived cell lines, before and after stimulation with 10µg/mL of PGN for 2 h *p < 0.05; **p < 0.01.