Table 2.

Definition of Candidate Predictors of Machine Learning Input Features

Category	Input Feature	Rationale for Inclusion in Testing
Timing	Late wasting	Wasting and administration delays could provide time for substitution or tampering. Late was defined as more than 4 hours after dispense.
	Late administration
Quantity	No administration	Failure to chart the total amount administered, wasted, and/or returned could be diversion. Wasting the full dose, or simultaneous wasting from multiple doses in bulk could indicate falsification of wasting records.
	Partial administration
	Partial waste/return
	Full wasting
	Bulk wasting
Practice	Handoffs	Gaps in chain of custody could provide opportunities for substitution or tampering. Administering medications in the wrong order or charting the wrong medication could indicate falsification of administration records.
	Incorrect order
	Incorrect medication