Table 4.

The details of genes that we mined by Deep-LC method.

Name	Entrez ID	References
KLK10	5655	Zhang et al. proved that KL10 was considerably downregulated in NSCLC compared to non-cancer samples. They concluded that KLK10 functions as a tumor suppressor gene in NSCLC, and epigenetic inactivation is a common occurrence in NSCLC pathogenesis that could be exploited as a biomarker (25).
DLEC1	9940	The study found that expression levels of DLEC1 were significantly different between tumor and normal tissues (p = 0.0001) (26).
EFEMP1	2202	EFEMP1 found a significantly higher frequency of methylation in NSCLC compared with the normal tissues (p ≤ 0.001) (27).

NSCLC, non-small cell lung cancer.