Table 4.
Correlation of hepatocyte nuclear factor 4 alpha and wingless-related integration site expression with types of gastric carcinomas according to WHO classification
| Groups | n |
Grade of HNF4α expression
|
Grade of WNT5a expression
|
|||||
|
+ (%)
|
++ (%)
|
+++ (%)
|
+ (%)
|
++ (%)
|
+++ (%)
|
|||
| Tubular | 35 | 4 (11.4) | 2 (5.7) | 29 (82.7)b | 2 (5.7) | 11 (31.4) | 22 (62.9) | |
| Signet ring | 59 | 5 (8.5) | 11 (18.6) | 43 (72.9) | 4 (6.8) | 17 (28.8) | 38 (64.4) | |
| Mucinous | 64 | 4 (6.3) | 7 (10.9) | 53 (82.8)b | 3 (4.7) | 10 (15.6) | 51 (79.7)d | |
b
P < 0.001 hepatocyte nuclear factor 4 alpha (χ2 = 83.909) vs signet ring.
d
P < 0.001 wingless-related integration site (χ2 = 105.865) vs tubular and signet ring.
HNF4α: Hepatocyte nuclear factor 4 alpha; WNT5A: Wingless-related integration site.