Table 5.
Correlation of hepatocyte nuclear factor 4 alpha and wingless-related integration site expression with types of gastric carcinomas according to Lauren classification
| Groups | n |
Grade of HNF4α expression
|
Grade of WNT5a expression
|
|||||
|
+ (%)
|
++ (%)
|
+++ (%)
|
+ (%)
|
++ (%)
|
+++ (%)
|
|||
| Intestinal | 97 | 11 (11.3) | 15 (15.5) | 71 (73.2) | 7 (7.2) | 23 (23.7) | 67 (69.1) | |
| Diffuse | 46 | 2 (4.4) | 5 (10.9) | 39 (84.8) | 2 (4.4) | 14 (30.4) | 30 (65.2) | |
| Mixed | 15 | 0 (0.00) | 0 (0.00) | 15 (100.0)b | 0 (0.00) | 1 (6.7) | 14 (93.3)d | |
b
P < 0.001 hepatocyte nuclear factor 4 alpha (χ2 = 79.404) vs intestinal and diffuse.
d
P < 0.001 wingless-related integration site (χ2 = 80.539) vs intestinal and diffuse.
HNF4α: Hepatocyte nuclear factor 4 alpha; WNT5A: Wingless-related integration site.