Table 3.
Docking results of the main active ingredients and core target molecules
|
Number
|
MAPK8/kaempferol Affinity (kcal/mol)
|
STAT3/licochalcone A Affinity (kcal/mol)
|
| 1 | -8.7 | -6.6 |
| 2 | -8.7 | -6.2 |
| 3 | -8.6 | -6 |
| 4 | -8.6 | -5.8 |
| 5 | -8.5 | -5.7 |
| 6 | -8.4 | -5.7 |
| 7 | -8.2 | -5.5 |
| 8 | -8 | -5.5 |
| 9 | -8 | -5.5 |
| 10 | -7.9 | -5.4 |
| 11 | -7.8 | -5.3 |
| 12 | -7.7 | -5.3 |
| 13 | -7.7 | -5.3 |
| 14 | -7.6 | -5.3 |
| 15 | -7.5 | -5.3 |
| 16 | -7.4 | -5.2 |
| 17 | -7.4 | -5.2 |
| 18 | -7.3 | -5.1 |
| 19 | -7.2 | -5.1 |
| 20 | -7.1 | -5 |
MAPK: Mitogen-activated protein kinase; STAT: Signal transducer and activator of transcription.