Table 4.

Sensitivity analysis with in-hospital mortality from intubation to hospital discharge

	Unadjusted* HR (95% CI)	P Value	Adjusted HR (95% CI)	P Value
Overcrowded ICU	1.43 (1.27–1.61)	<0.001	1.27 (1.12–1.44)	<0.001
Expanded ICU	1.20 (1.08–1.34)	<0.001	1.04 (0.93–1.17)	0.49
Age (yr)
<65	1 [Reference]		1 [Reference]
⩾65–<74	1.36 (1.19–1.55)	<0.001	1.26 (1.10–1.44)	<0.001
⩾75–<84	1.42 (1.23–1.64)	<0.001	1.36 (1.16–1.59)	<0.001
⩾85	2.59 (2.02–3.32)	<0.001	2.34 (1.79–3.04)	<0.001
Female	0.90 (0.80–1.02)	0.10	0.84 (0.74–0.95)	0.006
BMI
<30	1 [Reference]		1 [Reference]
⩾30 (obesity)	0.88 (0.79–0.99)	0.03	0.98 (0.87–1.10)	0.73
Missing data	2.31 (1.91–2.29)	<0.001	2.39 (1.97–2.91)	<0.001
Hypertension	1.15 (1.02–1.28)	0.02	1.07 (0.95–1.21)	0.29
Diabetes	1.13 (1.02–1.27)	0.03	1.10 (0.98–1.23)	0.13
Chronic heart disease	1.39 (1.20–1.62)	<0.001	1.26 (1.08–1.48)	0.005
Chronic lung disease	1.26 (0.96–1.63)	0.10	1.23 (0.94–1.62)	0.14
Time from admission until intubation (d)
<5	1 [Reference]		1 [Reference]
⩾5–<8	0.85 (0.70–1.02)	0.08	0.88 (0.73–1.06)	0.18
⩾8–<14	0.97 (0.82–1.15)	0.70	1.06 (0.89–1.26)	0.51
⩾14	1.19 (1.00–1.41)	0.04	1.27 (1.06–1.51)	0.01
Missing data	1.77 (1.45–2.16)	<0.001	1.78 (1.45–2.19)	<0.001
SAPS II, score points
<50	1 [Reference]		1 [Reference]
⩾50–<60	1.16 (0.97–1.38)	0.10	1.13 (0.95–1.35)	0.17
⩾60–<70	1.20 (1.01–1.43)	0.04	1.18 (0.99–1.40)	0.07
⩾70	1.48 (1.25–1.74)	<0.001	1.37 (1.16–1.63)	<0.001
Missing data	1.61 (1.30–2.01)	<0.001	1.52 (1.22–1.90)	<0.001

Definition of abbreviations: BMI = body mass index; CI = confidence interval; HR = hazard ratio; ICU = intensive care unit; SAPS II = Simplified Acute Physiology Score II.

^*Unadjusted model considers one variable of the model at a time.