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. 2020 Sep 16;33(3):127–135. doi: 10.1089/ped.2020.1196

Table 2.

Mean Asthma Control Test and Lung Functions (ppFEV1, ppFEF2575, and FEV1/FVC) by Treatment Groups Over Time (Mean ± SD)

Variables Baseline (mean ± SD)
3 months (mean ± SD)
6 months (mean ± SD)
9 months (mean ± SD)
1 year (mean ± SD)
Change over time (P) Difference between groups over time (P)
N = 148 N = 108 N = 67   N = 76
Asthma control test
 ICS 16.4 ± 5.5 20.8 ± 4.8 21.3 ± 5.3 19.2 ± 6.7 21.1 ± 4.4    
 ICS+LABA 14.2 ± 5.1 18.5 ± 5.6 19.9 ± 6.2 16.8 ± 6.4 18.2 ± 6.3 <0.0001 0.08
ppFEV1
 ICS 92.6 ± 15.6 96.8 ± 14.2 96.1 ± 14.5 92.0 ± 12.6 101.5 ± 14.5    
 ICS+LABA 88.2 ± 27.5 93.1 ± 10.7 89.8 ± 17.1 89.8 ± 17.1 90.6 ± 16.9 <0.0001 0.59
ppFEF2575
 ICS 89.0 ± 28.0 93.3 ± 22.3 104.1 ± 35.9 78.2 ± 22.7 100.3 ± 28.3    
 ICS+LABA 77.7 ± 30.7 85.6 ± 22.5 72.2 ± 23.9 78.3 ± 38.4 74.7 ± 21.7 0.02 0.62
FEV1/FVC
 ICS 87.9 ± 9.1 88.6 ± 7.9 90.1 ± 8.1 87.7 ± 12.4 90.6 ± 7.7    
 ICS+LABA 83.4 ± 10.9 85.7 ± 8.8 82.1 ± 10.4 77.7 ± 16.6 80.9 ± 9.9 0.12 0.47

SD, standard deviation.