Figure S2. Steady-state levels of fission machinery proteins in DNM1L patient fibroblasts.

Immunoblotting analysis of paediatric (C1 and C2) and adult controls (C3 and C4) and DNM1L P1 (p.Gly401Ser), P2 (p.Glys363Asp), P3 (p.Leu230dup), and P4 (p.Arg710Gly) patient fibroblasts showing the steady-state levels of DRP1 and MID51 proteins. The nuclear-encoded SDHA (Complex II) and β-actin were used as loading controls. Data information: Representative blots of three independent SDS–PAGE experiments are shown. Densitometric quantification of Western blots showing the mean % of relative band intensities between DNM1L patients (P1–P4) and control samples (SDHA–loading control, CP–paediatric control, CA–adult control). The error bars represent SD (n = 3).

Source data are available for this figure.