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. 2022 Jul 22;10:910353. doi: 10.3389/fchem.2022.910353

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Copyright © 2022 Li, Huang, Cheng, Xu, Qi, Dai, Yang, Tu, Peng and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of dual inhibition of HDAC and RAF pathway. Western blot analysis of 14b in HCT116 cells (A) and in HT-29 cells (B). Cells were treated with 0 μM, 0.12 μM, 0.37 μM, 1.1 μM, 3.3 μM, and 10 μM of drugs and incubated for 6 h. The cell lysis was subjected to Western blot analysis.