TABLE 3.

Selectivity of 14b and vorinostat in HDAC enzyme.

	Enzyme inhibition (μM)
Compound	Class I				Class IIA			Class IIB
	HDAC1	HDAC2	HDAC3	HDAC8	HDAC4	HDAC5	HDAC7	HDAC6
14b	0.493	0.747	0.913	3.004	>100	52.850	43.290	0.049
Vorinostat	0.030	0.091	0.056	1.380	>100	>100	89.200	0.014