TABLE 2.
Diagnostic ability of the DCS on different cognitive outcomes.
Cognitive outcomes | Cut-off | AUC (95% CI) | Sensitivity | Specificity | PPVb | NPVc |
NCIa vs. Dementia | ||||||
Automated scoring | 7/8 | 0.95 (0.90,0.99) | 100% | 80% | 50% | 100% |
Manual scoring | 7/8 | 0.99 (0.98,1.00) | 80.0% | 100% | 100% | 96.2% |
Dementia free vs. Dementia | ||||||
Automated scoring | 7/8 | 0.89 (0.81,0.98) | 100% | 62.4% | 22.2% | 100% |
Manual scoring | 7/8 | 0.90 (0.87,0.99) | 80.0% | 89.2% | 44.4% | 97.6% |
NCI vs. MCId | ||||||
Automated scoring | 8/9 | 0.77 (0.67,0.86) | 69.8% | 70.0% | 66.7% | 72.9% |
Manual scoring | 8/9 | 0.81 (0.73,0.90) | 51.2% | 92.0% | 84.6% | 68.7% |
NCI vs. CIe | ||||||
Automated scoring | 8/9 | 0.80 (0.72,0.89) | 75.5% | 70.0% | 72.7% | 72.9% |
Manual scoring | 8/9 | 0.84 (0.77,0.92) | 60.4% | 92.0% | 88.9% | 68.7% |
aNCI, no cognitive impairment; bPPV, positive predictive value; cNPV, negative predictive value; dMCI, mild cognitive impairment; eCI, cognitive impairment.