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. 2022 Jul 22;13:899729. doi: 10.3389/fpsyt.2022.899729

TABLE 2.

Diagnostic ability of the DCS on different cognitive outcomes.

Cognitive outcomes Cut-off AUC (95% CI) Sensitivity Specificity PPVb NPVc
NCIa vs. Dementia
Automated scoring 7/8 0.95 (0.90,0.99) 100% 80% 50% 100%
Manual scoring 7/8 0.99 (0.98,1.00) 80.0% 100% 100% 96.2%
Dementia free vs. Dementia
Automated scoring 7/8 0.89 (0.81,0.98) 100% 62.4% 22.2% 100%
Manual scoring 7/8 0.90 (0.87,0.99) 80.0% 89.2% 44.4% 97.6%
NCI vs. MCId
Automated scoring 8/9 0.77 (0.67,0.86) 69.8% 70.0% 66.7% 72.9%
Manual scoring 8/9 0.81 (0.73,0.90) 51.2% 92.0% 84.6% 68.7%
NCI vs. CIe
Automated scoring 8/9 0.80 (0.72,0.89) 75.5% 70.0% 72.7% 72.9%
Manual scoring 8/9 0.84 (0.77,0.92) 60.4% 92.0% 88.9% 68.7%

aNCI, no cognitive impairment; bPPV, positive predictive value; cNPV, negative predictive value; dMCI, mild cognitive impairment; eCI, cognitive impairment.